We are running the funding opportunity on the new UKRI Funding Service. You cannot apply for this opportunity on the Joint Electronic Submissions (Je-S) system.
The project lead is responsible for completing the application process on the Funding Service, but we expect all team members and project partners to contribute to the application.
Only the lead research organisation can submit an application to UKRI.
To apply:
Select ‘Start application’ near the beginning of this Funding finder page.
- Confirm you are the project lead.
- Sign in or create a Funding Service account. To create an account, select your organisation, verify your email address, and set a password. If your organisation is not listed, email support@funding-service.ukri.org
- Answer questions directly in the text boxes. You can save your answers and come back to complete them or work offline and return to copy and paste your answers. If we need you to upload a document, follow the upload instructions in the Funding Service. All questions and assessment criteria are listed in the How to apply section on this Funding finder page.
- Send the completed application to your research office for checking. They will return it to you if it needs editing.
- Your research office will submit the completed and checked application to UKRI.
Watch our research office webinars about the new UKRI Funding Service.
Deadline
We must receive your application by 26 September 2023 at 4:00pm UK time. You will not be able to apply after this time. We will not consider late applications.
You should ensure you are aware of and follow any internal institutional deadlines that may be in place.
Following the close of the funding opportunity, your application cannot be changed and applications will not be returned for amendment. If your application does not follow the guidance, it may be rejected.
Personal data
Processing personal data
MRC as part of UK Research and Innovation (UKRI), will need to collect some personal information to manage your funding service account and the registration of your funding applications. We may also need to share the application and any personal information that it contains with any lead agency applicable to your application, so that they can participate in the assessment process.
We will handle personal data in line with UK data protection legislation and manage it securely. For more information, including how to exercise your rights, read our privacy notice.
Publication of outcomes
MRC will publish the outcomes of this funding Opportunity at board and panel outcomes – MRC.
If your application is successful, some personal information will be published via the UKRI Gateway to Research.
UKRI Funding Service: section guidance
Summary
In plain English, provide a summary that can be sent to potential reviewers to determine if your proposal is within their field of expertise.
This summary may be made publicly available on external facing websites, so please ensure it can be understood by a variety of readers, for example:
- opinion-formers
- policymakers
- the general public
- the wider research community.
Guidance for writing a summary
Succinctly describe your proposed work in terms of:
- its context
- its aims and objectives
- its potential applications and benefits.
Word count: 550
Core team
List the key members of your team and assign them roles from the following:
- project lead (PL)
- project co-lead (UK) (PcL)
- project co-lead (international) (PcL (I))
- researcher co-lead
- grant manager
- research and innovation associate
- visiting researcher
- specialist
- technician
- professional enabling staff
Only list one individual as project lead.
Find out more about UKRI’s new grant roles and eligibility.
Section: MRC research area
Question: Select the primary MRC research area your application most closely aligns to.
In the text box, copy the number corresponding to your selected area:
Population and systems medicine
- cardiovascular medicine
- gastroenterology
- dentistry and orofacial medicine
- dermatology
- inflammation
- endocrinology
- metabolism and metabolic disease
- musculosketal
- nutrition
- obesity
- population health
- longitudinal population studies
- reproductive health
- maternal health including pregnancy and childbirth
- renal function and disease
- respiratory
- hepatic function and disease
- paediatrics and child health
- ageing
- multimorbidity
- rare diseases
- trauma
Cross-board areas
- data science and integration
- motor neurone disease
- myalgic encephalomyelitis/chronic fatigue syndrome
Additional guidance:
This is for administrative purposes to help with the initial application processing. We will check your choice and make a final decision on which board will lead the peer review of your application.
Word count: 1
Section: Lead agency applications
Question: Is your application using a lead agency agreement?
What assessors and looking for in your response
If not enter N/A in the text box
If your application is using a lead agency agreement (LAA), identify the agreement concerned by answering ‘Yes’ followed by ‘FAPESP’ or ‘FNR’:
- lead agency agreement with Luxembourg (FNR)
- lead agency agreement with Sao Paulo Research Foundation (FAPESP)
The assessors are looking for you to create and upload the required lead agency documents, to support your application. You must complete all the relevant documentation and attach it to this application as a single PDF.
FAPESP
FAPESP applicants must complete the FAPESP-specific forms:
Documents and guidance are available on the FAPESP website, including a FAPESP:
- consolidated budget form
- proposal form
- letter of eligibility
FNR
FNR applicants should complete the FNR-specific forms:
Documents and guidance are available on the FNR website, including:
- an INTER budget sheet
- an INTER budget justification
- an INTER budget plan
- FNR eligibility letter of support
You must also complete the project partners section, with information about the international research partner, including:
- international lead applicant contact name and organisation details
- contribution from the international funder (FAPESP or FNR)
Include the experience, skills and contributions of your international research partners in the response to Applicant and team capability to deliver.
You should ensure that you have read and understood the specific requirements for the LAA you are applying to, especially for costing the applications. Failure to comply with the specific LAA guidance may result in the rejection of your application.
You must submit the joint application to the international funder within seven days after your submission to MRC.
For general FAPESP guidance please see the FAPESP website.
For general FNR guidance please see the FNR website.
Word count: 50
Section: Vision and approach
You should upload the Vision and Approach document as a PDF.
The main document can be up to six pages, plus optional but recommended additional pages for:
- one-page diagrammatic workplan, such as a Gantt chart
- one page for reproducibility information
If recommended optional pages are completed the maximum length of the document is eight pages.
If you do not want to provide recommended optional information, or it is not relevant to your application, then you must limit the length of your document accordingly and not use optional pages for anything other than the specified purpose.
The document must have single line spacing, margins of at least 2cm and be typed using Arial 11pt, or another ‘sans serif’ font with an equivalent size to Arial 11pt.
Applications including vision and approach documents that do not comply with our requirements for length and content will be rejected.
Question: What are you hoping to achieve with and how will you deliver your proposed work?
What the assessors are looking for in your response
For the Vision, explain how your proposed work:
- is of excellent quality and importance within or beyond the fields or areas
- has the potential to advance current understanding, generates new knowledge, thinking or discovery within or beyond the field or area
- is timely given current trends, context and needs
- impacts world-leading research, society, the economy or the environment
Within the Vision section we also expect you to:
- identify the potential direct or indirect benefits and who the beneficiaries might be
- identify potential improvements in human or population health, whether through contributing to relieving disease or disability burden, improving quality of life or providing benefit to the health service or health-related industry
For the Approach, explain how you have designed your work so that it:
- is effective and appropriate to achieve your objectives
- is feasible, and comprehensively identifies any risks to delivery and how they will be managed
- if applicable, uses a clear and transparent methodology
- if applicable, summarises the previous work and describes how this will be built upon and progressed
- will maximise translation of outputs into outcomes and impacts
- describes how your, and if applicable your team’s, research environment (in terms of the place, its location, and relevance to the project) will contribute to the success of the work
Within the Approach section we also expect you to:
- demonstrate access to the appropriate services, facilities, infrastructure, or equipment to deliver the project
- provide a one-page project plan including milestones and timelines
- If applicable, specify population groups in relation to their diversity characteristics and the proposed analysis, following the MRC embedding diversity in research design policy
- If applicable, show how you will use both sexes in research involving animals and tissues and cells. If you are not proposing to do this, a strong justification is required
You have the option to provide one page of additional information about reproducibility and how you will ensure reliability and robustness of your work, such as further details of statistical analyses, methodology and experimental design.
The reproducibility information should be a clearly identified page in your vision and approach document. We expect you to seek professional statistical or other relevant advice in preparing your response, which may include:
- experimental approach to address objectives
- sample and effect sizes
- planned statistical analyses
- models chosen (for example animal model, cell line)
Refer to the MRC guidance for applicants, section 2.2.3.5 ‘Reproducibility and statistical design’, for further information, examples and online tools.
If your proposed work involves animals, and you provide information on animal sample sizes and statistical analyses in the vision and approach document, you should not duplicate it in the ‘Research involving the use of animals’ section, specifically within the experimental design and statistical framework section of the template. Use the ‘Research involving the use of animals’ section to provide information on the rationale for using animals, choice of species, welfare and procedure severity.
Word count: 10
Section: Applicant and team capability to deliver
Question: Why are you the right individual or team to successfully deliver the proposed work?
What the assessors are looking for in your response
Evidence of how you, and if relevant your team, have:
- the relevant experience (appropriate to career stage) to deliver the proposed work
- the right balance of skills and expertise to cover the proposed work
- the appropriate leadership and management skills to deliver the work and your approach to develop others
- contributed to developing a positive research environment and wider community
The word count for this section is 1,500 words, 1,000 words to be used for R4RI modules and, if necessary, a further 500 words for Additions. Use the Résumé for Research and Innovation (R4RI) format to showcase the range of relevant skills you, and if relevant your team (project lead and project co-leads, researchers, other (technical) staff for example research software engineers, data scientists and so on, and partners), have and how this will help to deliver the proposed work. You can include individuals’ specific achievements but only choose past contributions that best evidence their ability to deliver this work.
Complete this section using the R4RI module headings listed below. You should use each heading once and include a response for the whole team, see the UKRI guidance on R4RI. You should consider how to balance your answer, and emphasize where appropriate the key skills each team member brings:
- contributions to the generation of new ideas, tools, methodologies, or knowledge
- the development of others and maintenance of effective working relationships
- contributions to the wider research and innovation community
- contributions to broader research or innovation users and audiences and towards wider societal benefit
Additions: Provide any further details relevant to your application. This section is optional and can be up to 500 words. You should not use it to describe additional skills, experiences or outputs, but any factors that provide context for the rest of your R4RI (for example, details of career breaks if you wish to disclose them).
You should complete this as a narrative and you should avoid CV type format.
Word count: 1,500
Section: References
Question: List the references you’ve used to support your application.
What the assessors are looking for in your response:
You should include all references in this section of the application, and not in the rest of the application questions.
You should not include any other information in this section.
We advise you not to include hyperlinks, as assessors are not obliged to access the information they lead to or consider it in their assessment of your application.
If linking to web resources, to maintain the information’s integrity, include persistent identifiers (such as digital object identifiers) where possible.
You must not include links to web resources to extend your application.
Word count: 1,000
Section: Project partners: contributions
Question: Provide details of any project partners’ contributions, and letters or emails of support from each named partner.
What the assessors are looking for in your response
Download and complete the project partner contributions template (DOCX, 52KB). Include letters or emails of support from each partner in a single PDF.
Each letter or email you provide should:
- confirm the partner’s commitment to the project
- clearly explain the value, relevance, and possible benefits of the work to them
- describe any additional value that they bring to the project
The UKRI Funding Service will provide document upload details when you apply. If you do not have any project partners, you will be able to indicate this in the Funding Service.
Ensure you have prior agreement from project partners so that if you are offered funding, they will support your project as indicated in the template.
For audit purposes, UK Research and Innovation (UKRI) requires formal collaboration agreements to be put in place if an award is made.
Do not provide letters of support from host and project co-leads’ research organisations.
If your application includes industry project partners, you will also need to complete the Industry Collaboration Framework (ICF) section.
Find out more about ICF
Word count: 1,000
Section: Industry Collaboration Framework (ICF)
Question: Does your application include industry project partners?
What the assessors are looking for in your response
If industry collaboration does not apply to any of your project partners, or you don’t have any project partners, simply add ‘N/A’ into the text box.
If your research project involves collaboration between an academic organisation and an industry or company, you are likely to need to follow the industry collaboration framework and answer this question, check using the ICF decision tree.
By ‘industry or company’ we mean an enterprise that puts goods or services on a market and whose commercial activities are greater than 20% of their overall annual capacity.
The assessors are looking for information relating to the nature, goals and conditions of the collaboration and any restrictions or rights to the project results that could be claimed by the project partner.
Find out more about ICF, including:
- collaboration agreements
- definitions of basic or applied research
- internationally based companies
- subsidy control
- Intellectual property (IP) arrangements
- fully flexible and gated contributions
- the ICF assessment criteria
In addition to the project partner information completed in the previous section, confirm your answers to the ICF questions in the text box, repeat this process for each ICF project partner:
- Name the industry or company project partner considered under ICF.
- Indicate whether your application is either basic research or applied research.
- Explain why, in the absence of the requested UKRI funding, the collaboration and the planned research could not be undertaken.
- State whether your application is under the category of either fully flexible contribution or gated contribution (based on the IP sharing arrangements with the ICF partner).
- Outline the pre-existing IP (‘background IP’) that each project partner (including the academic partner) will bring to the collaborative research project and the terms under which project partners may access these assets.
- Outline the IP that is expected to be developed during the collaborative research project (‘foreground IP’) and briefly outline how it will be managed, including:
-
- which project partners will own this IP
- what rights project partners will have to use academically-generated foreground IP during and after the research project, for internal research and development or for commercial purposes
- any rights of the academic partner to commercialise the foreground IP (including foreground IP generated by project partners)
- Outline any restrictions to dissemination of the project results, including the rights of the project partner to:
-
- review, approve or delay publications (including the time period associated with such rights)
- request or require the removal of any information
- Declare any conflicts of interest held by the applicants in relation to the project partners and describe how they will be managed.
- If applicable, justify collaborating with an overseas industry or company under ICF.
Failure to provide the information requested for industry partners under ICF could result in your application being rejected.
You are recommended to discuss the goals and conditions of any collaboration with an industry or company project partner with your university technology transfer or contracts office before applying.
Word count: 1,500
Section: Facilities
Question: Does your proposed research require the support and use of a facility?
What the assessors are looking for in your response
If not, enter N/A into the text box, mark this section as complete and move on to the next section.
If you will need to use a facility, you should follow your proposed facility’s normal access request procedures. Where prior agreement is required, ensure you obtain their agreement that, should you be offered funding, they will support the use of their facility on your project.
In the text box below, for each requested facility you should provide:
- the name of facility, copied and pasted from this list
- the proposed usage or costs, or costs per unit where indicted on that list
- confirmation you have their agreement where required
Do not put the facility contact details in your response.
Word count: 250
Section: Data management and sharing
Question: how will you manage and share data collected or acquired through the proposed research?
What the assessors are looking for in your response
Provide a data management plan which should clearly detail how you will comply with MRC’s published data management and sharing policies, which includes detailed guidance notes. Provide your response following the MRC data management plan template.
The length of your plan will vary depending on the type of study being undertaken:
- Population cohorts; longitudinal studies; genetic, omics and imaging data; biobanks, and other collections that are potentially a rich resource for the wider research community: maximum of 1500 words
- For all other research, including less complex, the plan may be as short as 500 words
Word count: 1,500
Section: Ethics and Responsible Research and Innovation (RRI)
Question: What are the ethical or RRI implications and issues relating to the proposed work? If you do not think that the proposed work raises any ethical or RRI issues, explain why.
What the assessors are looking for in your response
Using the text box, demonstrate that you have identified and evaluated the relevant ethical or responsible research and innovation considerations, and how you will manage them.
Consider the MRC guidance on ethics and approvals.
If you are collecting or using data you should identify:
- any legal and ethical considerations of collecting, releasing or storing the data including consent, confidentiality, anonymisation, security and other ethical considerations and, in particular, strategies taken to not preclude further re-use of data
- formal information standards with which study will be compliant
Word count: 500
Section: Genetic and Biological Risk
Question: Does your proposed research involve any genetic or biological risk?
What the assessors are looking for in your response
If not, enter ‘N/A’ into the text box, mark this section as complete and move on to the next section.
In respect of animals, plants or microbes, are you proposing to:
- use genetic modification as an experimental tool, like studying gene function in a genetically modified organism
- release genetically modified organisms
- ultimately develop commercial and industrial genetically modified outcomes?
If yes, provide the name of any required approving body and state if approval is already in place. If it is not, provide an indicative timeframe for obtaining the required approval.
Identify the organism or organisms as a plant, animal or microbe and specify the species and which of the three categories the research relates to.
Identify the genetic and biological risks resulting from the proposed research, their implications and any mitigation you plan on taking. Assessors will want to know you have considered the risks and their implications to justify that any identified risks do not outweigh any benefits of the proposed research.
Word count: 700
Section: Research involving the use of animals
Question: Does your proposed research involve the use of vertebrate animals or other organisms covered by the Animals Scientific Procedures Act?
What the assessors are looking for in your response
If not, enter ‘N/A’ into the text box, mark this section as complete and do the same for the next question. If you are proposing research that requires using animals, write ‘Yes’ in the text box. Then, download and complete this document (DOCX, 74KB), which contains all the questions relating to research using vertebrate animals or other Animals (Scientific Procedures) Act 1986 regulated organisms. Then, save it as a PDF.
Word count 10
Section: Conducting research with animals overseas
Question: Will any of the proposed animal research be conducted overseas?
What the assessors are looking for in your response
If not, enter ‘N/A’ in the text box, mark as complete and move to the next question.
If you are proposing to conduct overseas research, it must be conducted in accordance with welfare standards consistent with those in the UK, as per Responsibility in the Use of Animals in Bioscience Research, on page 14.
You should also ensure all named applicants in the UK and overseas are aware of this requirement and provide a statement below to confirm that:
- all named applicants are aware of the requirements and have agreed to abide by them
- this overseas research will be conducted in accordance with welfare standards consistent with the principles of UK legislation
- the expectation set out in ‘Responsibility in the Use of Animals in Bioscience Research’ will be applied and maintained
- appropriate national and institutional approvals are in place.
Overseas studies proposing to use non-human primates, cats, dogs, equines or pigs, will be assessed during NC3Rs review of research proposals. The required information should be provided by completing the template from the question ‘Research Involving the use of animals’.
For studies involving other species listed below, you should select the relevant checklist or checklists from the list below, complete it and save it as a PDF and use the file upload feature to attach. If you need to complete more than one checklist, you should merge them into a single document and then save it as a PDF before uploading it.
Other species checklists:
Word count: 10
Section: Research involving human participation
Question: Will the project involve the use of human subjects or their personal information?
What the assessors are looking for in your response
If not, enter ‘N/A’ into the text box, mark this section as complete and move on to the next section.
If you are proposing research that requires the involvement of human subjects, provide the name of any required approving body and whether approval is already in place. Then, justify the number and the diversity of the participants involved, as well as any procedures.
Provide details of any areas of substantial or moderate severity of impact.
Word count: 700
Section: Research involving human tissues or biological samples
Question: Does your proposed research involve the use of human tissues, or biological samples?
What the assessors are looking for in your response
If not, enter ‘N/A’ into the text box, mark this section as complete and move on to the next section.
If you’re answering ‘yes’, provide the name of any required approving body and whether approval is already in place.
You should justify the use of human tissue or biological samples specifying the nature and quantity of the material to be used and its source.
Word count: 700
Section: Resources and cost justification
Question: What will you need to deliver your proposed work and how much will it cost?
What the assessors are looking for in your response
Use the resources and cost summary table to enter the full costs. Include high-level costs only, not a breakdown of individual items. Use the Justification text box to demonstrate how the resources you anticipate needing for your proposed work:
- are comprehensive, appropriate, and justified
- represent the optimal use of resources to achieve the intended outcomes
- maximise potential outcomes and impacts
This section should not simply be a list of the resources requested, as this will already be given in the detailed ‘costs’ table. Costings should be justified on the basis of full economic costs (FEC) of the project, not just on the costs expected from UKRI. For some items we do not expect you to justify the monetary value, rather the type of resource, such as amount of time or type of staff requested.
Where you do not provide adequate justification for a resource, we may deduct it from any funding awarded.
You should identify:
- support for activities to either increase impact, for public engagement, knowledge exchange or to support responsible innovation
- support for access to facilities, infrastructure or procurement of equipment
- support for preserving, long-term storage, or sharing of data
- support from your organisation or partner organisations and how that enhances value for money
- support for international co-leads, demonstrating this is within the 30% costs cap for co-leads from developed countries, India and China
- NHS research costs, when they are associated with NHS studies
- animal costs, such as numbers that need to be bred or maintained and to maintain high welfare standards
Word count 1,000
Section: Clinical research in the NHS, public health or social care
Question: Will your research take place in an NHS, public health or social care setting?
If not, enter ‘N/A’ into the text box
Researchers applying for clinical research in the NHS, public health or social care need to complete a Schedule of Events Cost Attribution Tool (SoECAT) to be eligible for the National Institute for Health Research (NIHR) Clinical Research Network (CRN) portfolio. This is the route through which support and excess treatment costs are provided in England.
You must answer ‘Yes’ and complete and upload a SoECAT if you are applying for clinical research funding, and:
- you will carry out your research in the UK
- it is intended for the NIHR CRN portfolio; this may include studies in a social care or public health setting
- the research requires approval by Health Research Authority (England) or its equivalents in Northern Ireland, Scotland or Wales
- your research will use NHS resources
You must complete a SoECAT even if you don’t think your clinical research will involve excess treatment costs (ETCs).
See MRC guidance 3.5.1 on who needs to complete a SoECAT
If you are applying for clinical research in the NHS, public health or social care and don’t think you need to complete a SoECAT, answer ‘Yes’ and explain why a SoECAT is not necessary.
We want to know that you have taken the appropriate steps for the full costs of your research to be attributed, calculated and paid.
We want to see the expected total resources required for your project, such as Excess Treatment Costs (ETCs), to consider if these are appropriate.
How to complete a SoECAT
SoECAT guidance can be found on the NIHR website
These are the steps you need to take:
- Contact an AcoRD specialist as early as possible in the application process.
- Complete an online SoECAT. Excel versions of the form have been discontinued. If you don’t have an account for NIHR’s Central Portfolio Management System (CPMS) you will need create and activate one. See the user guide for instructions.
- Request authorisation of your SoECAT.
- Once authorised convert the ‘summary’ page from the ‘Funder Export’ as a PDF and upload it to your application.
Applications that require a SoECAT but have not attached the SoECAT funder export summary may be rejected.
Contact support@funding-service.ukri.org if you have questions about the UKRI aspects of this process or have concerns that your SoECAT may not be authorised in time for the application deadline.
Word count: 250
Section: Related applications
Question: Is this application related to another application to MRC or other funding organisation?
What the assessors are looking for in your response
If not enter N/A
If yes, explain how this new application is related to the other application.
If the related application was submitted to another funder you should identify the name of the funder and when you applied.
If this is a resubmission describe how it differs from the previous application and how feedback on the previous application has been considered and acted on.
Word count: 500
