MRC has issued various sets of guidance concerning the use of animals in research, in addition to adopting policy and guidance from NC3Rs.
Home Office documents
- Animals (Scientific Procedures) Act 1986 (consolidated)
- Guidance on the Operation of the Act
- Home Office Code of practice for the care and accommodation of animals
Responsibility in the use of animals in bioscience research
General guidance for researchers using animals or animal research products in research and to those assessing applications for research funding.
MRC Guidance for applicants
- MRC guidance for applicants
- guidance for applicants for proposals involving animal use
- ARRIVE guidelines from the NC3Rs
- Experimental Design Assistant from the NC3Rs
- MRC worked examples of justifications for experimental design and animal number in grant applications
MRC Codes of Practice
- Code of practice for the supply of rodents in research (PDF, 43KB) (2006)
- Code of practice for the supply of aquatics in research (PDF, 49KB) (2007)
Sharing and archiving
- Sharing and archiving of genetically altered mice (PDF, 3.48MB)
- NC3Rs resource hub: Genetically altered mice
- frozen embryo and sperm archive (FESA)
- International Mouse Phenotyping Consortium
- MRC Centre for Macaques
- C3NRs guidelines on primate accommodation, care and use
- NC3Rs resource hub: the welfare of non-human primates
Other useful links
- European Animal Research Association (EARA)
- Fund for the Replacement of Animals in Medical Experiments (FRAME)
- Home Office: research and testing using animals
- Institute of Animal Technology (IAT)
- Laboratory Animal Science Association (LASA)
- MRC Harwell
- National Centre for the Replacement Refinement and Reduction of Animals in Research (NC3Rs)
- Royal Society for the Prevention of Cruelty to Animals (RSPCA)
- Understanding Animal Research (UAR)
- Talking about animals in research – if you are a researcher who would like advice about talking about your research, please contact the MRC communications team.
- Visiting an animal facility – if you are a journalist, please contact the MRC press office to arrange a visit. You will usually need to give a few days’ notice so they can arrange for a member of staff to give a tour and sterilise any equipment you need to bring. Some facilities can also accommodate small groups and schools.
Find out more about visiting a facility
Can I take photos and film inside the facility?
Yes, but please let us know in advance so that we can sterilise it for you. Our animal facilities are highly controlled to ensure that nothing comes in that could affect the animals’ health – we even filter the water coming into the building. Bear in mind that cleaning your equipment will take around 48 hours.
Will the cleaning process damage my camera?
We have never had an issue with the cleaning process damaging film or digital cameras. We clean equipment by putting it into a sealed chamber and pouring in vapourised hydrogen peroxide. We use the same process for our own equipment like fridges and freezers. The hydrogen peroxide cleans every surface and ensures the equipment is sterile and ready for you to use on the day.
I always clean my equipment carefully – do I still need to send it in?
Yes. We are committed to reducing the number of animals used in research as well as developing and using non-animal models. We use centralised animal facilities partly so that we know the only factors that change in the centre are to do with essential research. If dirt, infection or anything else that could affect the animals were to enter the building, researchers would no longer know whether results were accurate, and experiments might need to be repeated or even abandoned. By controlling these variables, we can use the smallest possible number of animals.
I have pets – can I still visit?
Let us know in advance and we can advise you. Requirements vary at different centres depending on the animals that live there – for example at the Mary Lyon Centre you must have had no contact with a rodent for 48 hours before you visit to protect the animals in the centre from infection.
What should I wear?
Bear in mind you will be asked to change into protective clothing before entering the centre. You will be provided with overshoes, overclothes, hair covers, beard covers and any other item necessary to protect the environment where the animals live.
UAR media centre – free resources, including the media centre with resources and links for journalists.
Documents which have been superseded by more up-to-date guidance can be found here for information.
Last updated: 26 August 2021